A case-control study to evaluate the impact of the breast screening programme on mortality in England.

ABSTRACT:

Background

Over the past 30 years since the implementation of the National Health Service Breast Screening Programme, improvements in diagnostic techniques and treatments have led to the need for an up-to-date evaluation of its benefit on risk of death from breast cancer. An initial pilot case-control study in London indicated that attending mammography screening led to a mortality reduction of 39%.

Methods

Based on the same study protocol, an England-wide study was set up. Women aged 47-89 years who died of primary breast cancer in 2010 or 2011 were selected as cases (8288 cases). When possible, two controls were selected per case (15,202 controls) and were matched by date of birth and screening area.

Results

Conditional logistic regressions showed a 38% reduction in

SUBMITTER: Maroni R 

PROVIDER: S-EPMC7884709 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature