The Changing Landscape of Pediatric Viral Enteropathogens in the Post-Rotavirus Vaccine Era.

ABSTRACT:

Background

Acute gastroenteritis (AGE) is a common reason for children to receive medical care. However, the viral etiology of AGE illness is not well described in the post-rotavirus vaccine era, particularly in the outpatient (OP) setting.

Methods

Between 2012 and 2015, children 15 days through 17 years old presenting to Vanderbilt Children's Hospital, Nashville, Tennessee, with AGE were enrolled prospectively from the inpatient, emergency department, and OP settings, and stool specimens were collected. Healthy controls (HCs) were enrolled and frequency matched for period, age group, race, and ethnicity. Stool specimens were tested by means of reverse-transcription real-time quantitative polymerase chain reaction for norovirus, sapovirus, and astrovirus RNA and by Rotaclone

SUBMITTER: Halasa N 

PROVIDER: S-EPMC7884803 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature