Mesoionic tetrazolium-5-aminides: Synthesis, molecular and crystal structures, UV-vis spectra, and DFT calculations.

ABSTRACT: Tetrazolium-5-aminides have been prepared by the tert-butylation of 5-aminotetrazole and its N-methyl derivatives by the t-BuOH/HClO₄ system followed by the treatment of the tetrazolium salts by alkali. The mesoionic compounds have been found to show a higher reactivity of the exocyclic N atom in comparison with 5-aminotetrazoles. The compounds reacted with 1,2-dibromoethane and 5-(methylsulfonyl)-1-phenyl-1H-tetrazole with substitution of bromine and methylsulfonyl groups giving the corresponding tetrazolium salts or conjugate aminides. The obtained mesoionic tetrazoles have been characterized by elemental analysis, FTIR, NMR, and UV-vis spectroscopy, TGA/DSC analysis and for 1,3-di-tert-butyltetrazolium-5-aminide, its N,N'-ethyl

SUBMITTER: Budevich VA 

PROVIDER: S-EPMC7884879 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature