Inflammatory Bowel Disease-Associated Changes in the Gut: Focus on Kazan Patients.

ABSTRACT:

Background

Several studies have highlighted the role of host-microbiome interactions in the pathogenesis of inflammatory bowel disease (IBD), resulting in an increasing amount of data mainly focusing on Western patients. Because of the increasing prevalence of IBD in newly industrialized countries such as those in Asia, the Middle East, and South America, there is mounting interest in elucidating the gut microbiota of these populations. We present a comprehensive analysis of several IBD-related biomarkers and gut microbiota profiles and functions of a unique population of patients with IBD and healthy patients from Kazan (Republic of Tatarstan, Russia).

Methods

Blood and fecal IBD biomarkers, serum cytokines, and fecal short-chain fatty acid (SCFA) content were profiled. Fin

SUBMITTER: Lo Sasso G 

PROVIDER: S-EPMC7885336 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature