Variation in chemical composition and antimalarial activities of two samples of Terminalia albida collected from separate sites in Guinea.

ABSTRACT:

Background

The disparity of harvesting locations can influence the chemical composition of a plant species, which could affect its quality and bioactivity. Terminalia albida is widely used in traditional Guinean medicine whose activity against malaria has been validated in vitro and in murine models. The present work investigated the antimalarial properties and chemical composition of two samples of T. albida collected from different locations in Guinea.

Method

T. albida samples were collected in different locations in Guinea, in Dubréka prefecture (West maritime Guinea) and in Kankan prefecture (eastern Guinea). The identity of the samples was confirmed by molecular analysis. In vitro antiplasmodial activity of the two extracts was determined against the chloroquine resista

SUBMITTER: Camara A 

PROVIDER: S-EPMC7885413 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature