Net ultrafiltration rate and its impact on mortality in patients with acute kidney injury receiving continuous renal replacement therapy.

ABSTRACT:

Background

Fluid overload, a critical consequence of acute kidney injury (AKI), is associated with worse outcomes. The optimal fluid removal rate per day during continuous renal replacement therapy (CRRT) is unknown. The purpose of this study is to evaluate the impact of the ultrafiltration rate on mortality in critically ill patients with AKI receiving CRRT.

Methods

This was a retrospective cohort study where we reviewed 1398 patients with AKI who received CRRT between December 2006 and November 2015 at the Mayo Clinic, Rochester, MN, USA. The net ultrafiltration rate (UF^NET) was categorized into low- and high-intensity groups (<35 and ≥35 mL/kg/day, respectively). The impact of different UF^NET intensities on 30-day mortality was assessed using logisti

SUBMITTER: Tehranian S 

PROVIDER: S-EPMC7886538 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature