Survival on four compared with three times per week haemodialysis in high ultrafiltration patients: an observational study.

ABSTRACT:

Background

The harm caused by the long interdialytic interval in three-times-per-week haemodialysis regimens (3×WHD) may relate to fluid accumulation and associated high ultrafiltration rate (UFR). Four-times-per-week haemodialysis (4×WHD) may offer a solution, but its impact on mortality, hospitalization and vascular access complications is unknown.

Methods

From the AROii cohort of incident in-centre haemodialysis patients, 3×WHD patients with a UFR >10 mL/kg/h were identified. The hazard for the outcomes of mortality, hospitalization and vascular access complications in those who switched to 4×WHD compared with staying on 3×WHD was estimated using a marginal structural Cox proportional hazards model. Adjustment included baseline patient and treatment characteristics with i

SUBMITTER: Fotheringham J 

PROVIDER: S-EPMC7886573 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature