Comparison of lipidome profiles of Caenorhabditis elegans-results from an inter-laboratory ring trial.

ABSTRACT:

Introduction

Lipidomic profiling allows 100s if not 1000s of lipids in a sample to be detected and quantified. Modern lipidomics techniques are ultra-sensitive assays that enable the discovery of novel biomarkers in a variety of fields and provide new insight in mechanistic investigations. Despite much progress in lipidomics, there remains, as for all high throughput "omics" strategies, the need to develop strategies to standardize and integrate quality control into studies in order to enhance robustness, reproducibility, and usability of studies within specific fields and beyond.

Objectives

We aimed to understand how much results from lipid profiling in the model organism Caenorhabditis elegans are influenced by different culture conditions in different laboratories.

Met

SUBMITTER: Spanier B 

PROVIDER: S-EPMC7886748 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature