Alterations in Dynamic Functional Connectivity in Individuals With Subjective Cognitive Decline.

ABSTRACT: Purpose: To investigate the dynamic functional connectivity (DFC) and static parameters of graph theory in individuals with subjective cognitive decline (SCD) and the associations of DFC and topological properties with cognitive performance. Methods: Thirty-three control subjects and 32 SCD individuals were enrolled in this study, and neuropsychological evaluations and resting-state functional magnetic resonance imaging scanning were performed. Thirty-three components were selected by group independent component analysis to construct 7 functional networks. Based on the sliding window approach and k-means clustering, distinct DFC states were identified. We calculated the temporal properties of fractional windows in each state, the mean dwell time in each state, and the number

SUBMITTER: Chen Q 

PROVIDER: S-EPMC7886811 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature