Insulinemic and Inflammatory Dietary Patterns and Risk of Prostate Cancer.

ABSTRACT:

Background

Hyperinsulinemia and inflammation are inter-related pathways that link diet with the risk of several chronic diseases. Evidence suggests that these pathways may also increase prostate cancer risk.

Objective

To determine whether hyperinsulinemic diet and inflammatory diet are associated with prostate cancer incidence and mortality.

Design, setting, and participants

We prospectively followed 41 209 men in the Health Professionals Follow-up Study (1986-2014). Scores for two validated dietary patterns were calculated from food frequency questionnaires at baseline and updated every 4 yr.

Outcome measurements and statistical analysis

Total, advanced, and lethal prostate cancer outcomes were assessed. Multivariable-adjusted hazard ratios (HRs) and 95% confi

SUBMITTER: Fu BC 

PROVIDER: S-EPMC7887049 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature