Virome composition in marine fish revealed by meta-transcriptomics.

ABSTRACT: Revealing the determinants of virome composition is central to placing disease emergence in a broader evolutionary context. Fish are the most species-rich group of vertebrates and so provide an ideal model system to study the factors that shape virome compositions and their evolution. We characterized the viromes of nineteen wild-caught species of marine fish using total RNA sequencing (meta-transcriptomics) combined with analyses of sequence and protein structural homology to identify divergent viruses that often evade characterization. From this, we identified twenty-five new vertebrate-associated viruses and a further twenty-two viruses likely associated with fish diet or their microbiomes. The vertebrate-associated viruses identified here included the first fish virus in the Matonav

SUBMITTER: Geoghegan JL 

PROVIDER: S-EPMC7887440 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature