A dynamic mammary gland model describing colostrum immunoglobulin transfer and milk production in lactating sows.

ABSTRACT: The physiology of the sow mammary gland is qualitatively well described and understood. However, the quantitative effect of various biological mechanisms contributing to the synthesis of colostrum and milk is lacking and more complicated to obtain. The objective of this study was to integrate physiological and empirical knowledge of the production of colostrum and milk in a dynamic model of a single sow mammary gland to understand and quantify parameters controlling mammary gland output. In 1983, Heather Neal and John Thornley published a model of the mammary gland in cattle, which was used as a starting point for the development of this model. The original cattle model was reparameterized, modified, and extended to describe the production of milk by the sow mammary gland during lactation

SUBMITTER: Krogh U 

PROVIDER: S-EPMC7887553 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature