Comparing mortality between positive and negative blood culture results: an inverse probability of treatment weighting analysis of a multicenter cohort.

ABSTRACT:

Background

The association between blood culture status and mortality among sepsis patients remains controversial hence we conducted a tri-center retrospective cohort study to compare the early and late mortality of culture-negative versus culture-positive sepsis using the inverse probability of treatment weighting (IPTW) method.

Methods

Adult patients with suspected sepsis who completed the blood culture and procalcitonin tests in the emergency department or hospital floor were eligible for inclusion. Early mortality was defined as 30-day mortality, and late mortality was defined as 30- to 90-day mortality. IPTW was calculated from propensity score and was employed to create two equal-sized hypothetical cohorts with similar covariates for outcome comparison.

Results

SUBMITTER: Liu A 

PROVIDER: S-EPMC7887786 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature