Impact of Body Habitus on the Outcomes of Pediatric Patients With Diabetic Ketoacidosis.

ABSTRACT:

Objective

To determine whether obese and overweight pediatric patients with new onset diabetic ketoacidosis (DKA) treated with continuous infusion insulin have increased time to subcutaneous insulin initiation or adverse events as compared with patients with normal body habitus.

Methods

A retrospective, cohort study was designed that included patients 2 to 18 years of age admitted with new onset DKA who received continuous infusion insulin from January 1, 2011, to December 31, 2017. Patients were stratified according to BMI percentile with the primary outcome of time to initiation of subcutaneous insulin. Secondary endpoints included time to minimum beta-hydroxybutyrate, and incidence of hypoglycemia or other adverse events.

Results

A total of 337 patients (46.6% male

SUBMITTER: Moffett BS 

PROVIDER: S-EPMC7887880 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature