Personalized genealogical history of UK individuals inferred from biobank-scale IBD segments.

ABSTRACT:

Background

The genealogical histories of individuals within populations are of interest to studies aiming both to uncover detailed pedigree information and overall quantitative population demographic histories. However, the analysis of quantitative details of individual genealogical histories has faced challenges from incomplete available pedigree records and an absence of objective and quantitative details in pedigree information. Although complete pedigree information for most individuals is difficult to track beyond a few generations, it is possible to describe a person's genealogical history using their genetic relatives revealed by identity by descent (IBD) segments-long genomic segments shared by two individuals within a population, which are identical due to inheritance from

SUBMITTER: Naseri A 

PROVIDER: S-EPMC7888130 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature