Latent Class Analysis: Insights about design and analysis of schistosomiasis diagnostic studies.

ABSTRACT: Various global health initiatives are currently advocating the elimination of schistosomiasis within the next decade. Schistosomiasis is a highly debilitating tropical infectious disease with severe burden of morbidity and thus operational research accurately evaluating diagnostics that quantify the epidemic status for guiding effective strategies is essential. Latent class models (LCMs) have been generally considered in epidemiology and in particular in recent schistosomiasis diagnostic studies as a flexible tool for evaluating diagnostics because assessing the true infection status (via a gold standard) is not possible. However, within the biostatistics literature, classical LCM have already been criticised for real-life problems under violation of the conditional independence (CI) assum

SUBMITTER: Koukounari A 

PROVIDER: S-EPMC7888681 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature