Unspecified stress disorders and risk of arterial and venous thromboembolic disease in the Danish population.

ABSTRACT:

Background

Posttraumatic stress disorder is a well-documented risk factor for cardiovascular disease. Whether non-specific stress-related psychopathology also increases risk is less well known.

Methods

In a cohort of adult Danish-born residents of Denmark with an incident diagnosis of unspecified reaction to severe stress ("unspecified stress reaction") between 1995 and 2011 (N = 24,534), we assessed incidence of seven arterial and venous cardiovascular events/conditions between 1996 and 2013. We calculated standardized incidence ratios (SIRs) comparing incidence of each outcome among the cohort to expected incidence based on sex-, age-, and calendar-time-specific national rates. We conducted stratified analyses by demographic characteristics, comorbidities, and length of fo

SUBMITTER: Smith ML 

PROVIDER: S-EPMC7889626 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature