Endemic chikungunya fever in Kenyan children: a prospective cohort study.

ABSTRACT:

Background

Chikungunya fever (CHIKF) was first described in Tanzania in 1952. Several epidemics including East Africa have occurred, but there are no descriptions of longitudinal surveillance of endemic disease. Here, we estimate the incidence of CHIKF in coastal Kenya and describe the associated viral phylogeny.

Methods

We monitored acute febrile illnesses among 3500 children visiting two primary healthcare facilities in coastal Kenya over a 5-year period (2014-2018). Episodes were linked to a demographic surveillance system and blood samples obtained. Cross-sectional sampling in a community survey of a different group of 435 asymptomatic children in the same study location was done in 2016. Reverse-transcriptase PCR was used for chikungunya virus (CHIKV) screening, and vir

SUBMITTER: Nyamwaya DK 

PROVIDER: S-EPMC7889702 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature