Evaluation of SUVlean consistency in FDG and PSMA PET/MR with Dixon-, James-, and Janma-based lean body mass correction.

ABSTRACT:

Purpose

To systematically evaluate the consistency of various standardized uptake value (SUV) lean body mass (LBM) normalization methods in a clinical positron emission tomography/magnetic resonance imaging (PET/MR) setting.

Methods

SUV of brain, liver, prostate, parotid, blood, and muscle were measured in 90 ¹⁸F-FDG and 28 ¹⁸F-PSMA PET/MR scans and corrected for LBM using the James, Janma (short for Janmahasatian), and Dixon approaches. The prospective study was performed from December 2018 to August 2020 at Shanghai East Hospital. Forty dual energy X-ray absorptiometry (DXA) measurements of non-fat mass were used as the reference standard. Agreement between different LBM methods was assessed by linear regression and Bland-Altman statistics. SUV's depe

SUBMITTER: Zhao J 

PROVIDER: S-EPMC7889776 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature