Association of History of Psychopathology With Accelerated Aging at Midlife.

ABSTRACT:

Importance

Individuals with mental disorders are at an elevated risk of developing chronic age-related physical diseases. However, it is not clear whether psychopathology is also associated with processes of accelerated aging that precede the onset of age-related disease.

Objective

To test the hypothesis that a history of psychopathology is associated with indicators of accelerated aging at midlife.

Design, setting, and participants

This prospective cohort study was based on the Dunedin Multidisciplinary Health and Development Study, a population-representative birth cohort of 1037 individuals born between April 1, 1972, and March 31, 1973, in Dunedin, New Zealand. Members were followed up to age 45 years (until April 2019). Data were analyzed from January 6 to Decemb

SUBMITTER: Wertz J 

PROVIDER: S-EPMC7890535 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature