Qualitative emphysema and risk of COPD hospitalization in a multicenter CT lung cancer screening cohort study.

ABSTRACT:

Background

In the United States, 9 to 10 million Americans are estimated to be eligible for computed tomographic lung cancer screening (CTLS). Those meeting criteria for CTLS are at high-risk for numerous cardio-pulmonary co-morbidities. The objective of this study was to determine the association between qualitative emphysema identified on screening CTs and risk for hospital admission.

Study design and methods

We conducted a retrospective multicenter study from two CTLS cohorts: Lahey Hospital and Medical Center (LHMC) CTLS program, Burlington, MA and Mount Auburn Hospital (MAH) CTLS program, Cambridge, MA. CTLS exams were qualitatively scored by radiologists at time of screening for presence of emphysema. Multivariable Cox regression models were used to evaluate the associ

SUBMITTER: Gazourian L 

PROVIDER: S-EPMC7890561 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature