Risk of contralateral breast cancer according to first breast cancer characteristics among women in the USA, 1992-2016.

ABSTRACT:

Background

Estimates of contralateral breast cancer (CBC) risk in the modern treatment era by year of diagnosis and characteristics of the first breast cancer are needed to assess the impact of recent advances in breast cancer treatment and inform clinical decision making.

Methods

We examined CBC risk among 419,818 women (age 30-84 years) who were diagnosed with a first unilateral invasive breast cancer and survived ≥ 1 year in the US Surveillance, Epidemiology, and End Results program cancer registries from 1992 to 2015 (follow-up through 2016). CBC was defined as a second invasive breast cancer in the contralateral breast ≥ 12 months after the first breast cancer. We estimated standardized incidence ratios (SIRs) of CBC by year of diagnosis, age at diagnosis, and tumor cha

SUBMITTER: Ramin C 

PROVIDER: S-EPMC7890613 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature