Timing of renal replacement therapy for patients with acute kidney injury: A systematic review and meta-analysis.

ABSTRACT:

Background

Acute kidney injury is associated with high mortality, and the optimal time to start renal replacement therapy for acute kidney injury is unknown despite several randomised controlled trials on the subject. We performed a systematic review and meta-analysis to assess the effect of earlier initiation of renal replacement therapy for acute kidney injury on mortality and reported secondary outcomes.

Methods

All literature in databases EMBASE, MEDLINE and CENTRAL was searched from January 1970 to March 2019 using terms related to renal replacement therapy, timing and randomised controlled trials. All randomised controlled trials with 25 or more adult participants suffering from acute kidney injury comparing timing of renal replacement therapy were included. The result

SUBMITTER: Andonovic M 

PROVIDER: S-EPMC7890756 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature