CeNet Omnibus: an R/Shiny application to the construction and analysis of competing endogenous RNA network.

ABSTRACT:

Background

The competing endogenous RNA (ceRNA) regulation is a newly discovered post-transcriptional regulation mechanism and plays significant roles in physiological and pathological progress. CeRNA networks provide global views to help understand the regulation of ceRNAs. CeRNA networks have been widely used to detect survival biomarkers, select candidate regulators of disease genes, and predict long noncoding RNA functions. However, there is no software platform to provide overall functions from the construction to analysis of ceRNA networks.

Results

To fill this gap, we introduce CeNet Omnibus, an R/Shiny application, which provides a unified framework for the construction and analysis of ceRNA network. CeNet Omnibus enables users to select multiple measurements, such a

SUBMITTER: Wen X 

PROVIDER: S-EPMC7890952 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature