MeltingPlot, a user-friendly online tool for epidemiological investigation using High Resolution Melting data.

ABSTRACT:

Background

The rapid identification of pathogen clones is pivotal for effective epidemiological control strategies in hospital settings. High Resolution Melting (HRM) is a molecular biology technique suitable for fast and inexpensive pathogen typing protocols. Unfortunately, the mathematical/informatics skills required to analyse HRM data for pathogen typing likely limit the application of this promising technique in hospital settings.

Results

MeltingPlot is the first tool specifically designed for epidemiological investigations using HRM data, easing the application of HRM typing to large real-time surveillance and rapid outbreak reconstructions. MeltingPlot implements a graph-based algorithm designed to discriminate pathogen clones on the basis of HRM data, producing porta

SUBMITTER: Perini M 

PROVIDER: S-EPMC7891011 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature