Effect of prior cancer on survival outcomes for patients with advanced prostate cancer.

ABSTRACT:

Background

A history of prior cancer commonly results in exclusion from cancer clinical trials. However, whether a prior cancer history has an adversely impact on clinical outcomes for patients with advanced prostate cancer (APC) remains largely unknown. We therefore aimed to investigate the impact of prior cancer history on these patients.

Methods

We identified patients with advanced prostate cancer diagnosed from 2004 to 2010 in the Surveillance, Epidemiology, and End Results (SEER) database. Propensity score matching (PSM) was used to balance baseline characteristics. Kaplan-Meier method and the Cox proportional hazard model were utilized for survival analysis.

Results

A total of 19,772 eligible APC patients were included, of whom 887 (4.5 %) had a history of prior

SUBMITTER: Wu Y 

PROVIDER: S-EPMC7891168 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature