Amplicon-based skin microbiome profiles collected by tape stripping with different adhesive film dressings: a comparative study.

ABSTRACT:

Background

Medical film dressings have been used to obtain skin microbiota for skin microbiome studies, although their adhesive force may be so strong that the skin could be injured when applied to those who have fragile skin, such as older people. Several products with less adhesive force are available, although their applicability for skin microbiome studies remains unknown. This study aimed to test whether the dressings with less adhesive force could be used for amplicon-based skin microbiome studies. A set of three different film dressings, with acrylic, urethane, or silicone adhesive, was applied to the back skin of nine healthy young participants. The copy number of the 16S ribosomal RNA (rRNA) gene, microbial compositions, and alpha and beta diversity indices were analyzed b

SUBMITTER: Ogai K 

PROVIDER: S-EPMC7891171 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature