Comparing Interventions for Management of Hot Flashes in Patients With Breast and Prostate Cancer: A Systematic Review With Meta-Analyses.

ABSTRACT:

Problem identification

Hot flashes are common and bothersome in patients with breast and prostate cancer and can adversely affect patients' quality of life.

Literature search

Databases were searched for randomized controlled trials (RCTs) evaluating the effects of one or more interventions for hot flashes in patients with a history of breast or prostate cancer.

Data evaluation

Outcomes of interest included changes in hot flash severity, hot flash frequency, quality of life, and harms. Pairwise meta-analyses and network meta-analyses were performed where feasible, with narrative synthesis used where required.

Synthesis

40 RCTs were included. Findings from network meta-analysis for hot flash frequency suggested that several therapies may offer benefits compared t

SUBMITTER: Hutton B 

PROVIDER: S-EPMC7891229 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature