Variability of Aldosterone Measurements During Adrenal Venous Sampling for Primary Aldosteronism.

ABSTRACT:

Background

Variability of aldosterone concentrations has been described in patients with primary aldosteronism.

Methods

We performed a retrospective cohort study of 340 patients with primary aldosteronism who underwent adrenal venous sampling (AVS) at a tertiary referral center, 116 of whom also had a peripheral venous aldosterone measured hours before the procedure. AVS was performed by the same interventional radiologist using bilateral, simultaneous sampling, under unstimulated and then stimulated conditions, and each sample was obtained in triplicate. Main outcome measures were: (i) change in day of AVS venous aldosterone from pre-AVS to intra-AVS and (ii) variability of triplicate adrenal venous aldosterone concentrations during AVS.

Results

Within an average dur

SUBMITTER: Yozamp N 

PROVIDER: S-EPMC7891268 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature