Impact of the Choice of Native T₁ in Pixelwise Myocardial Blood Flow Quantification.

ABSTRACT:

Background

Quantification of myocardial blood flow (MBF) from dynamic contrast-enhanced (DCE) MRI can be performed using a signal intensity model that incorporates T₁ values of blood and myocardium.

Purpose

To assess the impact of T₁ values on pixelwise MBF quantification, specifically to evaluate the influence of 1) study population-averaged vs. subject-specific, 2) diastolic vs. systolic, and 3) regional vs. global myocardial T₁ values.

Study type

Prospective.

Subjects

Fifteen patients with chronic coronary heart disease.

Field strength/sequence

3T; modified Look-Locker inversion recovery for T₁ mapping and saturation recovery gradient echo for DCE imaging, both acquired in a mid-ventricular short-axis slice

SUBMITTER: Krauter C 

PROVIDER: S-EPMC7891429 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature