Probe-based confocal laser endomicroscopy for pleural malignancies diagnosis.

ABSTRACT:

Background and objective

Probe based confocal laser endomicroscopy (pCLE) is an optical imaging technique allowing live tissue imaging at a cellular level. Currently, this tool remains experimental. Two studies regarding pleural disease have been published and suggest that pCLE could be valuable for pleural disease investigations. However, normal and malignant pleural pCLE features remain unknown. Therefore, we conducted a prospective trial of pCLE during medical thoracoscopy to study and describe the malignant and benign pleural pCLE features.

Methods

Every patient >18 years referred to our department for medical thoracoscopy was eligible. Medical thoracoscopy was performed under sedation, allowing spontaneous breathing. Five millilitres of fluorescein (10%) was intravenous

SUBMITTER: Bonhomme O 

PROVIDER: S-EPMC7891618 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature