Developmental outcomes in children exposed to Zika virus in utero from a Brazilian urban slum cohort study.

ABSTRACT:

Background

The prevalence of developmental alterations associated with in-utero Zika virus (ZIKV) exposure in children is not well understood. Furthermore, estimation of the Population Attributable Fraction (PAF) of developmental alterations attributed to ZIKV has not been performed due to lack of population-based cohorts with data on symptomatic and asymptomatic ZIKV exposures and an appropriate control group. The aim of this study was to characterize neurodevelopmental outcomes of children at 11 to 32 months of age with intrauterine ZIKV exposure and estimate the PAF of alterations secondary to ZIKV exposure.

Methodology/principal findings

We performed a cohort of biannual community-based prospective serosurveys in a slum community in Salvador, Brazil. We recruited women p

SUBMITTER: Aguilar Ticona JP 

PROVIDER: S-EPMC7891708 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature