Effect of combined acetylsalicylic acid and statins treatment on intracranial aneurysm rupture.

ABSTRACT:

Background

Acetylsalicylic acid (ASA) and statins have been identified as potentially reducing the risk of intracranial aneurysms (IA) rupture. We aim to determine the effect of this drugs on the risk of rupture of IA.

Patients and methods

We performed a retrospective cohort study from a prospective database of patients with IA treated in our institution between January 2013 and December 2018. Demographics, previous oral treatments, presence of multiple aneurysms, size of aneurysm, lobulation, location and morphology of the aneurysms were recorded. Patients were dichotomized as ruptured and unruptured IA.

Results

A total of 408 IA were treated, of which 283 (68.6%) were in women. The median age was 53, 194 (47.5%) were ruptured IA. 38 patients (9.3%) were receiving AS

SUBMITTER: Terceno M 

PROVIDER: S-EPMC7891751 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature