Factors associated with the progression of gastric intestinal metaplasia: a multicenter, prospective cohort study.

ABSTRACT: Background and study aims  Gastric cancer (GC) is usually preceded by premalignant gastric lesions (GPLs) such as gastric intestinal metaplasia (GIM). Information on risk factors associated with neoplastic progression of GIM are scarce. This study aimed to identify predictors for progression of GIM in areas with low GC incidence. Patients and methods  The Progression and Regression of Precancerous Gastric Lesions (PROREGAL) study includes patients with GPL. Patients underwent at least two upper endoscopies with random biopsy sampling. Progression of GIM means an increase in severity according to OLGIM (operative link on gastric intestinal metaplasia) during follow-up (FU). Family history and lifestyle factors were determined through questionnaires. Serum Helicobacter pylor

SUBMITTER: Nieuwenburg SAV 

PROVIDER: S-EPMC7892268 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature