Characterization of the Oral Microbiome of Medicated Type-2 Diabetes Patients.

ABSTRACT: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that is becoming a significant global health care problem. Several studies have shown that people with diabetes are more susceptible to oral problems, such as periodontitis and, although the causes are still inconclusive, oral microbiota is considered to play a major role in oral health. This study aimed to characterize the oral microbiome of a sample representing T2DM patients from Portugal and exploit potential associations between some microorganisms and variables like teeth brushing, smoking habits, average blood sugar levels, medication and nutrient intake. By sequencing the hypervariable regions V3-V4 of the 16S rRNA gene in 50 individuals belonging to a group of diabetes patients and a control group, we found a total of

SUBMITTER: Almeida-Santos A 

PROVIDER: S-EPMC7892904 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature