Cutting across structural and transcriptomic scales translates time across the lifespan in humans and chimpanzees.

ABSTRACT: How the unique capacities of human cognition arose in evolution is a question of enduring interest. It is still unclear which developmental programmes are responsible for the emergence of the human brain. The inability to determine corresponding ages between humans and apes has hampered progress in detecting developmental programmes leading to the emergence of the human brain. I harness temporal variation in anatomical, behavioural and transcriptional variation to determine corresponding ages from fetal to postnatal development and ageing, between humans and chimpanzees. This multi-dimensional approach results in 137 corresponding time points across the lifespan, from embryonic day 44 to approximately 55 years of age, in humans and their equivalent ages in chimpanzees. I used these data to

SUBMITTER: Charvet CJ 

PROVIDER: S-EPMC7893224 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature