Tuberculosis Exposure With Risk of Behcet Disease Among Patients With Uveitis.

ABSTRACT:

Importance

Although experimental studies support the hypothesis that exposure of infectious agents may trigger an aberrant immune response and contribute to noninfectious uveitis, the association of a definite pathogen with human noninfectious uveitis conditions appears not to have been well established in a population.

Objective

To evaluate associations of tuberculosis infection with risk of several noninfectious uveitis conditions.

Design, setting, and participants

These mendelian randomization and observational analyses were conducted with the genetic data of a Chinese cohort enrolled between April 2008 and January 2018 and a Japanese cohort enrolled between January 2002 and June 2009. We recruited participants for T-SPOT.TB (Oxford Immunotec) assays between July a

SUBMITTER: Zhong Z 

PROVIDER: S-EPMC7893545 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature