Comparison of different detection methods for Mycoplasma pneumoniae infection in children with community-acquired pneumonia.

ABSTRACT:

Background

Due to the lack of a sensitive, specific and rapid detection method, aetiological diagnosis of pneumonia caused by Mycoplasma pneumoniae (M. pneumoniae, MP) is a constantly challenging issue. This retrospective study aimed to compare the diagnostic methods for Mycoplasma pneumoniae in children and evaluate their values.

Methods

From November 2018 to June 2019, 830 children with community-acquired pneumonia were selected from the Department of Respiratory Medicine, Shanghai Children's Medical Center. On the first day of hospitalization, sputum, throat swab and venous blood samples were collected to analyse MP-IgM (particle agglutination, PA), MP-IgM (immune colloidal gold technique, GICT), MP-DNA, MP-RNA (simultaneous amplification and testing, SAT) and MP-DNA (rea

SUBMITTER: Tang M 

PROVIDER: S-EPMC7893926 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature