Prone positioning in mechanically ventilated patients with severe acute respiratory distress syndrome and coronavirus disease 2019.

ABSTRACT:

Background

The management of COVID-19 ARDS is debated. Although current evidence does not suggest an atypical acute respiratory distress syndrome (ARDS), the physiological response to prone positioning is not fully understood and it is unclear which patients benefit. We aimed to determine whether proning increases oxygenation and to evaluate responders.

Methods

This case series from a single, tertiary university hospital includes all mechanically ventilated patients with COVID-19 and proning between 17 March 2020 and 19 May 2020. The primary measure was change in PaO₂ :FiO₂ .

Results

Forty-four patients, 32 males/12 females, were treated with proning for a total of 138 sessions, with median (range) two (1-8) sessions. Median (IQR) time for the fi

SUBMITTER: Gleissman H 

PROVIDER: S-EPMC7894343 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature