Cerebral Blood Flow in Patients with Severe Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation.

ABSTRACT:

Background

Transcatheter aortic valve implantation (TAVI) is a minimally invasive, life-saving treatment for patients with severe aortic valve stenosis that improves quality of life. We examined cardiac output and cerebral blood flow in patients undergoing TAVI to test the hypothesis that improved cardiac output after TAVI is associated with an increase in cerebral blood flow.

Design

Prospective cohort study.

Setting

European high-volume tertiary multidisciplinary cardiac care.

Participants

Thirty-one patients (78.3 ± 4.6 years; 61% female) with severe symptomatic aortic valve stenosis.

Measurements

Noninvasive prospective assessment of cardiac output (L/min) by inert gas rebreathing and cerebral blood flow of the total gray matter (mL/100 g per min) usi

SUBMITTER: Vlastra W 

PROVIDER: S-EPMC7894507 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature