Stress and Mindfulness in Parkinson's Disease: Clinical Effects and Potential Underlying Mechanisms.

ABSTRACT: Patients with Parkinson's disease (PD) are very vulnerable to the negative effects of psychological distress: neuropsychiatric symptoms, such as anxiety and depression, are highly prevalent in PD; motor symptoms (such as tremor) typically worsen in stressful situations; and dopaminergic medication is less effective. Furthermore, animal studies of PD suggest that chronic stress may accelerate disease progression. Adequate self-management strategies are therefore essential to reduce the detrimental effects of chronic stress on PD. Mindfulness-based interventions encourage individuals to independently self-manage and adapt to the challenges created by their condition. In PD, emerging clinical evidence suggests that mindfulness-based interventions may reduce psychological distress and improve

SUBMITTER: van der Heide A 

PROVIDER: S-EPMC7894549 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature