Whole-Volume Tumor MRI Radiomics for Prognostic Modeling in Endometrial Cancer.

ABSTRACT:

Background

In endometrial cancer (EC), preoperative pelvic MRI is recommended for local staging, while final tumor stage and grade are established by surgery and pathology. MRI-based radiomic tumor profiling may aid in preoperative risk-stratification and support clinical treatment decisions in EC.

Purpose

To develop MRI-based whole-volume tumor radiomic signatures for prediction of aggressive EC disease.

Study type

Retrospective.

Population

A total of 138 women with histologically confirmed EC, divided into training (n_T = 108) and validation cohorts (n_V = 30).

Field strength/sequence

Axial oblique T₁ -weighted gradient echo volumetric interpolated breath-hold examination (VIBE) at 1.5T (71/138 patients) and DIXON VIBE at

SUBMITTER: Fasmer KE 

PROVIDER: S-EPMC7894560 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature