Protective impacts of household-based tuberculosis contact tracing are robust across endemic incidence levels and community contact patterns.

ABSTRACT: There is an emerging consensus that achieving global tuberculosis control targets will require more proactive case finding approaches than are currently used in high-incidence settings. Household contact tracing (HHCT), for which households of newly diagnosed cases are actively screened for additional infected individuals is a potentially efficient approach to finding new cases of tuberculosis, however randomized trials assessing the population-level effects of such interventions in settings with sustained community transmission have shown mixed results. One potential explanation for this is that household transmission is responsible for a variable proportion of population-level tuberculosis burden between settings. For example, transmission is more likely to occur in households in setting

SUBMITTER: Havumaki J 

PROVIDER: S-EPMC7895355 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature