Closing delivery gaps in the treatment of tuberculosis infection: Lessons from implementation research in Peru.

ABSTRACT:

Background

Targeted testing and treatment of TB infection to prevent disease is a pillar of TB elimination. Despite recent global commitments to greatly expand access to preventive treatment for TB infection, there remains a lack of research on how best to expand preventive treatment programs in settings with high TB burdens.

Methods

We conducted implementation research in Lima, Peru, around a multifaceted intervention to deliver TB preventive treatment to close contacts of all ages, health care workers, and people in congregate settings. Key interventions included use of the interferon gamma release assay (IGRA), specialist support for generalist physicians at primary-level health facilities, and treatment support by community health workers. We applied a convergent mixed m

SUBMITTER: Yuen CM 

PROVIDER: S-EPMC7895363 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature