Health and Economic Outcomes Associated with Polio Vaccine Policy Options: 2019-2029.

ABSTRACT: The polio endgame remains complicated, with many questions about future polio vaccines and national immunization policies. We simulated possible future poliovirus vaccine routine immunization policies for countries stratified by World Bank Income Levels and estimated the expected costs and cases using an updated integrated dynamic poliovirus transmission, stochastic risk, and economic model. We consider two reference cases scenarios: one that achieves the eradication of all wild polioviruses (WPVs) by 2023 and one in which serotype 1 WPV (WPV1) transmission continues. The results show that the addition of inactivated poliovirus vaccine (IPV) to routine immunization in all countries substantially increased the expected costs of the polio endgame, without substantially increasing its expecte

SUBMITTER: Kalkowska DA 

PROVIDER: S-EPMC7895457 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature