Rate of detection of serrated lesions at colonoscopy in an average-risk population: a meta-analysis of 129,001 individuals.

ABSTRACT: Background and study aims  Serrated lesions are precursors of approximately one-third of colorectal cancers (CRCs). Information on their detection rate was lacking as an important reference for CRC screening. This study was a systematic review and meta-analysis to determine the overall detection rate for serrated lesions and their subtypes in average-risk populations undergoing CRC screening with colonoscopy. Patient and methods  MEDLINE and Embase were searched to identify population-based studies that reported the detection rate for serrated lesions. Studies on average-risk populations using colonoscopy as a screening tool were included. Metaprop was applied to model within-study variability by binomial distribution, and Freeman-Tukey Double Arcsine Transformation was adopt

SUBMITTER: Huang J 

PROVIDER: S-EPMC7895666 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature