Bridging the Age Gap in breast cancer: Impact of chemotherapy on quality of life in older women with early breast cancer.

ABSTRACT:

Introduction

Older patients with early breast cancer (EBC) derive modest survival benefit from chemotherapy but have increased toxicity risk. Data on the impact of chemotherapy for EBC on quality of life in older patients are limited, but this is a key determinant of treatment acceptance. We aimed to investigate its effect on quality of life in older patients enrolled in the Bridging the Age Gap study.

Materials and methods

A prospective, multicentre, observational study of EBC patients ≥70 years old was conducted in 2013-2018 at 56 UK hospitals. Demographics, patient, tumour characteristics, treatments and adverse events were recorded. Quality of life was assessed using the European Organisation for Research and Treatment of Cancer Quality-of-Life Questionnaires (EORTC-QLQ)

SUBMITTER: Battisti NML 

PROVIDER: S-EPMC7896040 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature