Direct differentiation of whole blood for forensic serology analysis by thread spray mass spectrometry.

ABSTRACT: Direct analysis of whole blood on bloodstained textiles is achieved with thread spray mass spectrometry (MS). This capability satisfies investigators' first priority in crime scene investigations, which is determining if a stain is blood. This thread spray method explores the use of evidentiary fabric threads for rapid determination of hemoglobin directly from whole blood within textiles without prior extraction steps. The multiplicity of information that can be derived from the thread spray MS method distinguishes it from the current presumptive Bluestar® method, by enabling the detection of hemoglobin (both α- and β-chains), the heme co-factor and lipids all from a single blood sample. Lipid composition was found to differ for blood samples originating from human, canine, and horse speci

SUBMITTER: Jackson S 

PROVIDER: S-EPMC7896278 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature