An Algorithm for Gene Fragment Reconstruction.

ABSTRACT: Gene sequencing technology has been playing an important role in many aspects, such as life science, disease medicine and health medicine, particularly in the extremely tough process of fighting against 2019-novel coronavirus. Drawing DNA restriction map is a particularly important technology in genetic biology. The simplified partial digestion method (SPDP), a biological method, has been widely used to cut DNA molecules into DNA fragments and obtain the biological information of each fragment. In this work, we propose an algorithm based on 0-1 planning for the location of restriction sites on a DNA molecule, which is able to solve the problem of DNA fragment reconstruction just based on data of fragments' length. Two specific examples are presented in detail. Furthermore, based on 1000 gr

SUBMITTER: Fang N 

PROVIDER: S-EPMC7896547 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature