4D Printing of shape-memory polymeric scaffolds for adaptive biomedical implantation.

ABSTRACT: 4D printing has shown great potential in a variety of biomedical applications due to the adaptability and minimal invasiveness of fabricated devices. However, commonly employed shape memory polymers (SMPs) possess undesirable transition temperatures (T_transs), leading to complications in implantation operations. Herein, we demonstrate 4D printing of a new SMP named poly(glycerol dodecanoate) acrylate (PGDA) with a T_trans in a range of 20 °C - 37 °C making it appropriate for shape programming at room temperature and then shape deployment within the human body. In addition, the material possesses suitable rheological properties to allow for the fabrication of a variety of delicate 3D structures such as "triangular star", "six-petal flower", "honeycomb", "tube", tilted "

SUBMITTER: Zhang C 

PROVIDER: S-EPMC7897283 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature